Compounds derived from Dimethyl benzoic acid or a Salt thereof, Selective inhibitors of EP4； Pharmaceutical composition that is useful for the treatment of osteoarthritis, Rheumatoid Arthritis and Pain associated with osteoarthritis or rheumatoid arthritis.
VETMAN TATIANA NATALI,BLANCO-PILLADO MARIA-JESUS,FISHER MATTHEW JOSEPH,KUKLISH STEVEN LEE
申请号：
CL2014003537
公开号：
CL2014003537A1
申请日:
2014.12.26
申请国别(地区):
CL
年份:
2015
代理人:
摘要：
The present invention provides a compound of the Formula II: wherein A is: R1 is CH3, CF3, or F； R2 is H, CH3, or F； R3 is CH3, OCH3, OH, F； R4 is OH or CH2OH； and X is CH or N； or a pharmaceutically acceptable salt thereof.COMPUESTOS DERIVADOS DE ÁCIDO DIMETIL BENZOICO, INHIBIDORES SELECTIVOS DE EP4； FORMA CRISTALINA； COMPOSICIÓN FARMACÉUTICA QUE LOS COMPRENDE； Y SU USO PARA EL TRATAMIENTO DE OSTEOARTRITIS, ARTRITIS REUMATOIDE, Y DOLOR ASOCIADOS A OSTEOARTRITIS Y ARTRITIS REUMATOIDE.
