Tao GONG,Xu SONG,Zhirong ZHANG,Yan ZHANG,Guangfei WEI,Mei HU,Tijia CHEN,Xun SUN,Yao FU
申请号：
US16489353
公开号：
US20200069583A1
申请日:
2017.10.11
申请国别(地区):
US
年份:
2020
代理人:
摘要：
An in situ phase change gel sustained-release preparation for a small molecule drug and a preparation method thereof. The in situ phase change gel sustained-release preparation comprises a small molecule drug comprising an active pharmaceutical ingredient, a phospholipid, Span, and an ethanol solution. The in situ phase change gel sustained-release preparation has a high concentration of phospholipids combined with Span, and is thus able to reduce the immediate-release of the small molecule drug and extend the release time, and is suitable for various administration routes, such as subcutaneous injection and external administration.
