Yang, Wu,Corte, James R.,Gilligan, Paul J.,Pinto, Donald J.P. Pinto,Ewing, William R.,Wang, Yufeng
申请号:
AU2013296258
公开号:
AU2013296258A1
申请日:
2013.08.02
申请国别(地区):
AU
年份:
2015
代理人:
摘要:
The present invention provides compounds of Formula (VIII): or stereoisomers, tautomers, or pharmaceutically acceptable salts thereof, wherein all the variables are as defined herein. These compounds are selective factor XIa inhibitors or dual inhibitors of FXIa and plasma kallikrein. This invention also relates to pharmaceutical compositions comprising these compounds and methods of treating thromboembolic and/or inflammatory disorders using the same.