YANG Wu,YANG Wu,CORTE James R.,CORTE James R.,GILLIGAN Paul J.,GILLIGAN Paul J.,PINTO Donald J.P. Pinto,PINTO Donald J.P. Pinto,EWING William R.,EWING William R.,DILGER Andrew K.,DILGER Andrew K.,WANG
申请号:
SI201330570
公开号:
SI2880026T1
申请日:
2013.08.02
申请国别(地区):
SI
年份:
2017
代理人:
摘要:
The present invention provides compounds of Formula (X):(Formula (X), or stereoisomers, tautomers, or pharmaceutically acceptable salts thereof, wherein all the variables are as defined herein. These compounds are selective factor XIa inhibitors or dual inhibitors of FXIa and plasma kallikrein. This invention also relates to pharmaceutical compositions comprising these compounds and methods of treating thromboembolic and/or inflammatory disorders using the same.