Hector F. DeLuca,Izabela K. Sibilska,Rafal R. Sicinski,Lori A. Plum
申请号：
US15220035
公开号：
US09688596B2
申请日:
2016.07.26
申请国别(地区):
US
年份:
2017
代理人:
摘要：
Disclosed are 2-methylene analogs of vitamin D3 and related compounds, their biological activities, and various pharmaceutical uses for these analogs. Particularly disclosed are 1α-hydroxy-2-methylene-vitamin D3, (20S)-1α-hydroxy-2-methylene-vitamin D3, and (5E)-1α,25-dihydroxy-2-methylene-vitamin D3, their biological activities, and various pharmaceutical uses for these compounds including methods of treating and/or preventing bone diseases and disorders.
