Provided herein are methods of treating, preventing and/or managing cancers, which comprise administering to a patient 3-(5-amino-2-methyl-4-oxo-4H-quinazolin-3-yl)-piperidine-2,6-dione, or an enantiomer or a mixture of enantiomers thereof, or a pharmaceutically acceptable salt, solvate, hydrate, co-crystal, clathrate, or polymorph thereof.本發明係關於治療、預防及/或處理癌症之方法,其包括向患者投與3-(5-胺基-2-甲基-4-氧基-4H-喹唑啉-3-基)-六氫吡啶-2,6-二酮或其對映異構體或對映異構體之混合物、或其醫藥學上可接受之鹽、溶劑合物、水合物、共晶體、籠合物或多晶型物。