A method for isolating one compound or more than one compounds from a biomass which contains microorganisms that have produced the compound or compounds, the method comprising the following steps: (a) preparing or obtaining wet cells having an average moisture content of between 30% and 80%; (b) subjecting the wet cells to primary drying to obtain primary dried cells having an average moisture content of between 5% and 50%; (c) subjecting the primary dried cells obtained in (b) to secondary drying to obtain secondary dried cells having an average moisture content of no greater than 10%; and (d) extracting or isolating purifying and/or refining the compound or each of the compounds from the secondary dried cells obtained in (c).一種用以自一微生物質量分離一或多於一化合物之方法,該微生物質量係包含已生產該或該等化合物之微生物,該方法係包含下列步驟:(a)製備或獲得具有一平均濕含量落在30-80%之間的濕細胞;(b)將該濕細胞引入第一階段乾燥來獲得具有一平均濕含量落在5-50%之間的第一階段乾燥細胞;(c)將該第一階段乾燥細胞引入第二階段乾燥來獲得具有一平均濕含量不超過10%的第二階段乾燥細胞;以及(d)自該由(c)獲得之第二階段乾燥細胞來萃取或分離、純化及/或精製該或該等之個別化合物。