１７－羥基－１７－五氟乙基－雌甾－４，９（１０）－二烯－１１－芳基衍生物、其製造方法及其治療疾病之用途农业专利-农业学术服务平台

发明人:: SCHWEDE, WOLFGANG,先威德　沃夫根,KLAR, ULRICH,可拉　乌瑞区,可拉　烏瑞區,MOELLER, CARSTEN,莫勤　卡斯坦,ROTGERI, ANDREA,罗格瑞　安卓拉,羅格瑞　安卓拉,BONE, WILHELM,波恩　威尔翰,波恩　威爾翰,先威德沃夫根,可拉乌瑞区,可拉烏瑞區,莫勤卡斯坦,罗格瑞安卓拉,羅格瑞安卓拉,波恩威尔翰,波恩威爾翰

摘要：: The invention relates to 17-hydroxy-17-pentafluoroethyl-estra-4,g(10)-dien-11-aryl derivatives of Formula I with progesterone antagonizing action and method of production thereof, use thereof for the treatment and/or prophylaxis of diseases and use thereof for the production of medicinal products for the treatment and/or prophylaxis of diseases, in particular of fibroids of the uterus (myomas, uterine leiomyoma), endometriosis, heavy menstrual bleeds, meningiomas, hormone-dependent breast cancers and complaints associated with the menopause or for fertility control and emergency contraception.本發明係關於一種具孕酮拮抗作用之如通式I之17-羥基-17-五氟乙基-雌甾-4,9(10)-二烯-11-芳基衍生物；及其製造方法；及其用於治療及/或預防疾病之用途；及其用於製造用於治療及/或預防疾病(特定言之子宮肌瘤(myomas、uterine leiomyoma)、子宮內膜異位症、嚴重經期出血、腦膜瘤、激素依賴性乳癌及與停經相關之併發症)，或用於節育及緊急避孕之藥品上之用途。