Jogeshwar Mukherjee,Aparna Baranwal,Nehal Mahendra Shah
申请号:
US14522905
公开号:
US20150291647A1
申请日:
2014.10.24
申请国别(地区):
US
年份:
2015
代理人:
摘要:
Various compositions and methods for Quasi-Amadori products and derivatives thereof are contemplated in which a halogenated carbohydrate is reacted with a primary amino group of an affinity ligand. In especially preferred aspects, the Quasi-Amadori product is formed from 2-fluorodeoxyglucose and an affinity moiety that preferentially or selectively binds to a neural cell or neural structure. Where contemplated compounds include 18F, PET imaging using compounds presented herein is especially preferred.