Nutritional compositions that include calcium ?-hydroxy-?-methylbutyrate and protein, and methods of using and making the nutritional compositions are provided. Casein phosphopeptide is utilized to sequester the calcium ?-hydroxy- ?-methylbutyrate to reduce the interaction between the divalent calcium ions and protein in the nutritional composition to improve the overall S stability, shelf life, and viscosity of the nutritional composition, while also facilitating the absorption of calcium.