Disclosed are nanoencapsulated compositions with long-acting/slow-release properties and improved safety and efficacy profiles, for repelling insects and other arthropod pests away from animals, including humans. Also disclosed are methods of preparing the nanoparticle formulations. In a particular embodiment, the formulations comprising as an active ingredient a coumarin derivative (EV6062 or EV06062) The formulations also prevent illness and disease caused by insect/pest-borne vectors, and provide safer, more effective alternatives to existing repellents.
