Victor J. TORRES,Derya UNUTMAZ,Francis ALONZO, III
申请号：
US15273888
公开号：
US20170224768A1
申请日:
2016.09.23
申请国别(地区):
US
年份:
2017
代理人:
摘要：
The present invention relates to methods for preventing or treating Human Immunodeficiency Virus (HIV) infection, inflammatory conditions, and graft-versus-host-disease (GVHD) in a subject. Therapeutic compositions of the present invention comprise Leukocidin E (LukE) and/or D proteins or polypeptides. The invention further relates to methods of treating Staphylococcus aureus infection by administering a composition comprising a CCR5 antagonist or any molecule that blocks LukE/D interaction with CCR5+ cells in an amount effective to treat the S. aureus infection in the subject.
