A method for customizing an interactive control boundary based on a patient-specific anatomy includes obtaining a standard control boundary and determining an intersection between a reference feature associated with the standard control boundary and a virtual representation of an anatomy of the patient. The method further includes identifying an anatomic perimeter at the intersection between the identified reference feature and the virtual representation of the anatomy. An anatomic feature on the virtual representation of the anatomy is determined from the intersection of the reference feature and the virtual representation of the anatomy. The standard control boundary is modified based on at least one anatomic feature to generate a customized control boundary.