KLUGE, Stefan;GRÜNENTHAL GMBH;GRUß, Michael;PRÜHS, Stefan
发明人:
GRUß, Michael,KLUGE, Stefan,PRÜHS, Stefan
申请号:
EPEP2012/002839
公开号:
WO2013/007361A9
申请日:
2012.07.06
申请国别(地区):
EP
年份:
2013
代理人:
摘要:
The present invention relates to crystalline forms of (1r,4r)-6'-fluoro-N,N-dimethyl-4-phenyl-4',9'-dihydro-3'l-l-spiro[cyclohexane-1,1 '-pyrano[3,4,b]indol]-4-amine, pharmaceutical compositions and medicaments comprising these modifications, the use of these modifications as well as to a process for the enrichment of them.L'invention concerne des formes cristallines de (1r,4r)-6'-fluoro-N,N-diméthyl-4-phényl-4',9'-dihydro-3'H-spiro[cyclohexane-1,1'-pyrano[3,4,b]indol]-4-amine, des compositions pharmaceutiques et des médicaments contenant ces modifications, l'utilisation de ces modifications, ainsi qu'un procédé d'enrichissement associé.