Disclosed is a herbicide composition, which is highly safe to a useful crop, and which can control various weeds that may cause troubles in a paddy, an agricultural field, a cropland or the like at any stage falling within a wide weed growth range from a pre-germination stage to a growing stage. A herbicide composition which comprises a component A comprising at least one compound selected from the group consisting of an isoxazoline derivative represented by the formula [I] and a salt thereof and a component B-13 as active ingredients. Component A:wherein R1 and R2 independently represent a hydrogen atom, a C1-C10 alkyl group, a C3-C8 cycloalkyl group or a C3-C8 cycloalkyl-C1-C3 alkyl group, and R3 and R4 independently represent a hydrogen atom, a C1-C10 alkyl group or a C3-C8 cycloalkyl group, provided that R1, R2, R3 and R4, together with a carbon atom to which these groups is bound, may form a 5- to 8-membered ring; R5 and R6 independently represent a hydrogen atom or a C1-C10 alkyl group; Y represents a 5- to 6-membered aromatic heterocyclic group or aromatic hetero fused ring group having one heteroatom selected from the group consisting of a nitrogen atom, an oxygen atom and a sulfur atom. Component B-13: fatty acids synthesis inhibitors selected from the group comprising: a) thiocarbamates: butylate, cycloate, dimepiperate, EPTC, esprocarb, molinate, orbencarb, pebulate, prosulfocarb, thiobencarb, tiocarbazil, triallate, vernolate; b) benzofuran derivatives: benfuresate, ethofumesate, c) chlorocarboxylic acid derivatives: TCA, dalapon, flupropanate; d) dithiophosphates: bensulide.Предлагается гербицидная композиция, которая является высокобезопасной для сельскохозяйственных растений и которая способна бороться с сорняками, проблемными, например, в рисовых полях, суходольных полях или на несельскохозяйственных землях в широком диапазоне от периода до всходов до периода после всходов. Гербицидная композиция содержит следующий компонент А, который представляет