LEIGHTON, Harry J.,BUDERER, Matthew J.,FRANGAKIS, Crist J.
申请号:
AU20160256779
公开号:
AU2016256779(B2)
申请日:
2016.11.10
申请国别(地区):
澳大利亚
年份:
2018
代理人:
摘要:
Abstract: The present invention relates to, among other things, methods for treating trigeminal cephalgias such as migraine and migraine like headaches and other cerbrovascular conditions associated with pain and or inflammation. When non-steroidal anti inflammatory drugs (NSAIDs), such as ketoprofen, are applied locally using specific topical formulations immediate relief of pain is obtained. Intense pain is typically reduced to mild pain or no pain within 30 minutes of application of the topical formulation. The NSAID may be given in combination with other pharmacological agents, such as vasoconstrictors, opioids, decongestants and/or non-opioid migraine drugs, such as triptans and ergots and agents that affect serotonin receptors as agonists, antagonists or partial agonists.