Frankfurt Am Main;Johann Wolfgang Goethe-Universitat
发明人:
Zeiher, Andreas,Dimmeler, Stefanie,Boon, Reinier
申请号:
AU2011234453
公开号:
AU2011234453A1
申请日:
2011.04.01
申请国别(地区):
AU
年份:
2012
代理人:
摘要:
The present invention relates to antagonists of the expression and/or the function of the micro RNA miRNA-29 for use in the prevention and/or treatment of aortic aneurysms. Further disclosed is a method for the identification of miRNA-29 antagonists, a pharmaceutical composition comprising said miRNA-29 antagonists and a method for preventing and treating age-related aortic aneurysm formation in a subject in need of such a treatment.