A binocular loupe containing one or more sealed fluid filled lenses is described. The binocular loupe includes one or more eyepieces, a distance sensor, and control electronics. In an embodiment, the optical power of the fluid filled lenses may be adjusted to adjust the focal length associated with the binocular loupe. The distance sensor may be used to determine a distance between the binocular loupe and a sample while a controller compares the measured distance to the current optical power of the one or more sealed fluid filled lenses. The controller may transmit signals to one or more actuators coupled to one or more sealed fluid filled lenses to change the optical power of the one or more sealed fluid filled lenses based on the comparison.