The user activated fluid path connection 300 includes a connection hub 310, a piercing member 330, a sterilization sleeve 320, a drug container 50 having a cap 52, a pierceable seal 56, a barrel 58 and a plunger seal 60. The member is initially held in a sterile sleeve between the connection hub and the pierceable seal of the drug container. The connection hub 3310 may include an internal opening 3310D in the connection hub, the internal opening functions as a flow restrictor, the piercing member 3330 is connected to one end of the internal opening, and the fluid conduit 3030 is connected to the other end of the internal opening. Is done. A drug delivery pump 10 with sterility maintenance function includes a housing 12 on which is connected to an activation mechanism 14, an insertion mechanism 200, the fluid path connection described above, a power supply / control system 400, and a drug container. The drive mechanism 100 is attached. An assembly method and an operation method are also provided. [Selection] Figure 3Bユーザ起動式の流体経路接続部３００は、接続ハブ３１０と、穿孔部材３３０と、滅菌スリーブ３２０と、キャップ５２、穿孔可能シール５６、バレル５８およびプランジャシール６０を有する薬剤容器５０とを含み、穿孔部材は、最初は、接続ハブと薬剤容器の穿孔可能シールとの間で滅菌スリーブ内に保持される。接続ハブ３３１０は該接続ハブ内に内部開口３３１０Ｄを含んでもよく、内部開口が流量制限器として機能し、穿孔部材３３３０が内部開口の一端に接続され、流体導管３０３０が内部開口の他端に接続される。滅菌性維持機能を伴う薬剤送達ポンプ１０はハウジング１２を含み、ハウジング上には、起動機構１４、挿入機構２００、前述した流体経路接続部、電源・制御システム４００、および、薬剤容器に接続される駆動機構１００が装着される。組み立て方法および動作方法も提供される。【選択図】図３Ｂ
