UNIVERSITATSMEDIZIN DER JOHANNES GUTENBERG-UNIVERSITAT MAINZ
发明人:
SCHMITT, EDGAR,KUNZ, HORST,STERGIOU, NATASCHA,GAIDZIK, NIKOLA
申请号:
CA3094127
公开号:
CA3094127A1
申请日:
2019.03.18
申请国别(地区):
CA
年份:
2019
代理人:
摘要:
The present invention relates to a compound comprising - a first polypeptide sequence comprising at least three different amino acid sequences selected from the group consisting of GFTFSDYW (SEQ ID NO: 1), IRLKSNNYAA (SEQ ID NO: 2) and TFGNSFAY (SEQ ID NO: 3), - a second polypeptide sequence comprising at least three different amino acid sequences selected from the group consisting of TGAVTTNNY (SEQ ID NO: 4), GTN (SEQ ID NO: 5) and ALWYSNHWV (SEQ ID NO: 6), or a variant of any one of said amino acid sequences of SEQ ID NO: 1 to SEQ ID NO: 6 having a different amino acid at one position, wherein said compound or variant is capable of binding to tumour-associated Mucin- (TA-MUC1).