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KINASE INHIBITORS
专利权人:
Respivert Limited;Topivert Pharma Limited
发明人:
Matthew Colin Thor FYFE,Stephen Malcolm THOM
申请号:
US16021519
公开号:
US20180305383A1
申请日:
2018.06.28
申请国别(地区):
US
年份:
2018
代理人:
摘要:
There are provided compounds of:wherein T, A, Q, Z, R4, R5a, R5b, n, r, Het1 and Rx have meanings given in the description, which compounds are useful in synthesizing compounds that have antiinflammatory activity (e.g., through inhibition of one or more of members of: the family of p38 mitogen-activated protein kinase enzymes; Syk kinase; and members of the Src family of tyrosine kinases) and have use in therapy, including in pharmaceutical combinations, especially in the treatment of inflammatory diseases, including inflammatory diseases of the lung, eye and intestines.
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