BEAUMONT TIM,KWAKKENBOS MARK JEROEN,BROWN ERIC J,MORISAKI JOHN HIROSHI,HAZENBOS WOUTER L.W,MARIATHASAN SANJEEV,KAJIHARA KIMBERLY,XIA YI
申请号：
NZ59806310
公开号：
NZ598063A
申请日:
2010.07.15
申请国别(地区):
NZ
年份:
2014
代理人:
摘要：
Disclosed is an isolated antibody comprising: a)a heavy chain CDR1 sequence RFAMS (SEQ ID NO:1)； b)a heavy chain CDR2 sequence STNNGNNPYYARSVQY (SEQ ID NO:2) or SINSGNNPYYARSVQY (SEQ ID NO:60)； c)a heavy chain CDR3 sequence DHPSSGWPTFDS (SEQ ID NO:3)； d)a light chain CDR1 sequence RASENVGDWLA (SEQ ID NO:4)； e)a light chain CDR2 sequence KTSILES (SEQ ID NO:5)； and f)a light chain CDR3 sequence having at least 88% identity to QHYXRFPYT, wherein X is any amino acid. Also disclosed is the use of said antibody in the manufacture of a medicament for treating gram-positive bacterium related disorders.
