DENNIS G. BERRY,PAUL A. MARTINSON,RYAN PATRICK SIMMERS
申请号：
US14905018
公开号：
US20160151617A1
申请日:
2014.07.10
申请国别(地区):
US
年份:
2016
代理人:
摘要：
An article 100 having a first side 112 that has a central portion 130 defined by a first edge 134, a microneedle-free peripheral portion 140 that substantially surrounds the central portion, and a plurality of spaced-apart hollow microneedles 160. Each microneedle has a body that includes an outer surface 163 a base segment 166 having a base 162 and a first shape a tip segment 168 having a tip 164 and a second shape, wherein the second shape is distinct from the first shape a transition plane 167 that delineates the base segment and the tip segment and a central axis 180. An angle, defined by an intersection of the central axis of at least one microneedle and a shortest line extending from the first edge and through the transition plane of the at least one microneedle, is less than about 50°.
