ASHOK CHANDRA ILLAPAKURTHY,SRIKANTA PATRA,VARMA S RUDRARAJU
申请号:
IN3370/CHE/2013
公开号:
IN2013CH03370A
申请日:
2013.07.29
申请国别(地区):
IN
年份:
2015
代理人:
摘要:
The present invention relates to a pharmaceutical composition comprising rivaroxaban or a pharmaceutically acceptable salt thereof, and a surfactant wherein the rivaroxaban is co-micronized with the surfactant. The rivaroxaban and surfactant is present in a molar ratio from about 0.1:1 to 1:0.1. The co-micronized rivaroxaban and surfactant mixture has a mean particle size less than 30um. The invention also relates to the methods of preparation of the composition and method of administration.