PROBLEM TO BE SOLVED: To provide an internal or external use composition which inhibits a maillard reaction occurring in a living body, more concretely, inhibits a dry change of skin, the lowering of skin transparency, a diabetic cataract, and malfunctions of a blood vessel or a renal function.SOLUTION: The composition contains a tranexamic acid as an effective compound. The composition also suppress the dry change of the skin or the lowering of the transparency of the skin.COPYRIGHT: (C)2013,JPO&INPIT【課題】生体内で起こるメイラード反応を抑制する内服または外用剤組成物を提供する。より詳しくは、AGEsの蓄積に起因する、皮膚褐変や肌透明度低下、糖尿病性の白内障、血管障害または腎機能障害を抑制する。【解決手段】トラネキサム酸を有効成分として含有する。【選択図】なし