Jane E. Clifford,Oleg Alekseev,Stephen R. Jennings
申请号:
US14488980
公开号:
US20150080390A1
申请日:
2014.09.17
申请国别(地区):
US
年份:
2015
代理人:
摘要:
The present invention relates generally to compositions and methods for treating diseases and disorders caused by herpes simplex virus type 1, including herpes simplex keratitis, in a subject. In certain embodiments, the compositions of the present invention comprise an ATM inhibitor and an anti-herpetic agent. In other embodiments, the compositions comprise a Chk2 inhibitor and an anti-herpetic agent. In yet other embodiments, the compositions comprise a Chk2 inhibitor and an ATM inhibitor, and optionally an anti-herpetic agent.