Jane E. CLIFFORD,Oleg ALEKSEEV,Stephen R. JENNINGS
申请号:
US15679642
公开号:
US20180008609A1
申请日:
2017.08.17
申请国别(地区):
US
年份:
2018
代理人:
摘要:
The present invention relates generally to compositions and methods for treating diseases and disorders caused by herpes simplex virus type 1, including herpes simplex keratitis, in a subject. In certain embodiments, the compositions of the present invention comprise an ATM inhibitor and an anti-herpetic agent. In other embodiments, the compositions comprise a Chk2 inhibitor and an anti-herpetic agent. In yet other embodiments, the compositions comprise a Chk2 inhibitor and an ATM inhibitor, and optionally an anti-herpetic agent.