The present invention provides a method for treating cancer in a subject, or reduction of tumor volume, inhibition or delay of tumor growth, inhibition of tumor progression, alteration of tumor metabolic activity, induction of tumor dormancy, inhibition of metastasis. Or methods of inducing anti-tumor effects including inhibition, inhibition or inhibition of tumor invasion, reduction of tumor weight, inhibition of tumor angiogenesis, improvement of time to disease progression (TDP), and / or improvement of survival rate To do. The method includes administering to the subject an effective amount of angiogenin or an angiogenin agonist. [Selection] Figure 1本発明は、被験体において癌を治療するための方法、又は、腫瘍体積の減少、腫瘍増殖の阻害又は遅延、腫瘍進行の阻害、腫瘍の代謝活性の変化、腫瘍の休眠の誘発、転移の阻害又は抑制、腫瘍浸潤の阻害又は抑制、腫瘍重量の減少、腫瘍血管新生の抑制、疾患進行までの時間（ＴＤＰ）の改善、及び／又は生存率の向上を含む抗腫瘍作用を誘発する方法を提供する。該方法は、被験体に有効量のアンギオゲニン又はアンギオゲニンアゴニストを投与することを含む。【選択図】図１
