用於治療癌症的PD-1拮抗劑和RAF抑制劑的組合农业专利-农业专业知识服务系统

发明人:: LI, KANG,李　康,SONG, JING,宋兢,ZHANG, TONG,张彤,張彤,LUO, LUSONG,罗侣松,羅侶松,WEI, MIN,魏旻,TANG, TRISTIN,汤志宇,湯志宇,WANG, LAI,汪　来,汪　來,ZHANG, GUOLIANG,张国良,張國良,ZHOU, CHANGYOU,周　昌友,李康,汪来,汪來,周昌友

摘要：: Disclosed herein is a pharmaceutical combination for use in the prevention, delay of progression or treatment of cancer, wherein the pharmaceutical combination exhibits a synergistic efficacy. The pharmaceutical combination comprises a humanized antagonist monoclonal antibody against PD-1 and a RAF inhibitor. Also disclosed herein is a combination for use in the prevention, delay of progression or treatment of cancer in a subject, comprising administering to the subject a therapeutically effective amount of a humanized antagonist monoclonal antibody against PD-1 and a therapeutically effective amount of a RAF inhibitor.本申請公開了用於預防癌症、延緩癌症進展或治療癌症的藥物組合，其中所述藥物組合展現出協同功效。所述藥物組合包含針對PD-1的人源化拮抗劑單克隆抗體和RAF抑制劑。本申請還公開了用於在受試者中預防癌症、延緩癌症進展或治療癌症的方法，其包括向所述受試者施用治療有效量的針對PD-1的人源化拮抗劑單克隆抗體和治療有效量的RAF抑制劑。