DOLUTEGRAVIR CALCIUM

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专利权人:

发明人:

SINGH GIRIJ PAL,SHRIVASTAVA DHANANJAI,JADHAV HARISHCHANDRA SAMBHAJI,CHAUDHARI NAMRATA ANIL,CHAVAN UDAY TANAJI

申请号：

IN1640/MUM/2015

公开号：

IN2015MU01640A

申请日:

2015.04.22

申请国别(地区):

IN

年份:

2017

代理人:

摘要：

The present invention encompasses a process for preparation of dolutegravir calcium, which comprises mixing dolutegravir sodium in organic solvent, adding aqueous calcium chloride solution and isolating dolutegravir calcium. The present invention further encompasses a process for preparation of a polymorphic form of dolutegravir calcium, which comprises mixing dolutegravir sodium in organic solvent, adding aqueous calcium chloride solution, isolating crude dolutegravir calcium, washing with water and isolating a polymorphic form of dolutegravir calcium.

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中国工程科技知识中心

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