The present invention relates to a method for the preparation of a granulate of at least two active constituents, comprising a step of applying the active constituents by powdering to a solid particulate support, the active constituents not being plant extracts.本發明係關於一種用於製備具有至少兩種活性組份的顆粒之方法,其包含藉由撒粉方式將該活性組份施加於固態微粒載體之步驟,該活性組份並非植物萃出物。