AMIT SINGH,Prof Pramod Kumar Sharma,Dr Dipak Kanti Majumdar
申请号:
IN201611019323
公开号:
IN201611019323A
申请日:
2016.06.05
申请国别(地区):
IN
年份:
2016
代理人:
摘要:
In the present study we were able to encapsulate fluconazole in vesicles like liposomes, niosomes and PLGA-nanospheres. The observed responses were in close agreement with the predicted value of optimized formulation that demonstrated the feasibility of the optimization procedure in developing vesicles and nano-sized formulations. The optimized, designed systems have been found reasonably well in their characteristics like size, shape, entrapment, loading, polydispersity index, stability, microbiological assay, ex- vivo and in-vivo performance.