JIN, YE,MURPHY, JOHN E.,HERMISTON, TERRY,MYLES, TIMOTHY,DITTMER, FRANK,STRERATH, MICHAEL,GRITZAN, UWE
申请号：
CA2916421
公开号：
CA2916421A1
申请日:
2014.03.14
申请国别(地区):
CA
年份:
2014
代理人:
摘要：
This patent document relates to antibodies, antigen-binding antibody fragments (Fabs), and other protein scaffolds, directed against human antithrombin ß complexed with heparin and/or heparin-like structure (??ß?). These ??ß? binding proteins can block the anti-coagulant activity of ??ß to induce coagulation. Therapeutic uses of these antibodies and binders are described herein as are methods of panning and screening specific antibodies.
