ANILLO VAGINAL QUE COMPRENDE DHEA O DHEA SULFATO Y OPCIONALMENTE UN AGENTE MODULADOR DE LA LIBERACION DEL PRINCIPIO ACTIVO, UTIL PARA AUMENTAR LA RESERVA OVARICA EN MUJERES Y PARA ALIVIAR SINTOMAS ASOCIADOS A LA MENOPAUSIA.
Shu-Chen CHEN,Frans Ariel FUENTES GARCÍA,Marianela Del Carmen BELTRÁN APABLAZA
申请号：
MX2014007957
公开号：
MX350336B
申请日:
2011.12.29
申请国别(地区):
MX
年份:
2017
代理人:
摘要：
The invention relates to a sustained-release vaginal ring which includes dehydroepiandrosterone (DHEA), dehydroepiandrosterone sulphate (DHEA-S) or a pharmaceutically acceptable salt thereof as an active principle and, optionally, an agent modulating the release of the active principle, in which the amount of the active principle is between 1 wt % and 32 wt % in relation to the total weight of the formulation, and the modulating agent is selected between: polyvinylpyrrolidone K-30, lactose, microcrystalline cellulose and sodium lauryl sulphate. The vaginal ring of the present invention can be used to increase the ovarian reserve in women, to be used as a drug in assisted reproduction programmes and to relieve symptoms associated with menopause, such as symptoms of vulvar and vaginal atrophy and sexual dysfunction in post-menopausal women.La presente invención se refiere a un anillo vaginal de liberación sostenida, caracterizado porque comprende de 1% a 32% en peso, en relación al peso total de la formulación, de dehidroepiandrosterona como agente activo, y de 2% a 25% en peso, en relación al total de la formulación, de polivinilpirrolidona K-30 como modulador de la liberación del agente activo.
