Richard Pastor;Bing-Yan Zhu;Christopher Hurley;Zhao Junping;Zheng Jifu;Michael Siu;Joseph P. Lyssikatos;He Haiying;Xu Xing;Steven R. Magnuson;Wendy Liu;Xiao Yisong;Jun Liang
发明人:
Bing-Yan Zhu,Michael Siu,Steven R. Magnuson,Richard Pastor,He Haiying,Xiao Yisong,Zheng Jifu,Xu Xing,Zhao Junping,Christopher Hurley,Jun Liang,Wendy Liu,Joseph P. Lyssikatos
申请号：
US13471269
公开号：
US20120225855A1
申请日:
2012.05.14
申请国别(地区):
US
年份:
2012
代理人:
摘要：
A compound of Formula I, enantiomers, diasteriomers, tautomers or pharmaceutically acceptable salts thereof, wherein R1, R2, R3, R4 and R5 are defined herein, are useful as JAK kinase inhibitors. A pharmaceutical composition that includes a compound of Formula I and a pharmaceutically acceptable carrier, adjuvant or vehicle, and methods of treating or lessening the severity of a disease or condition responsive to the inhibition of JAK kinase activity in a patient are disclosed.
