ZHU BING-YAN,SIU MICHAEL,MAGNUSON STEVEN R,PASTOR RICHARD D,HAIYING HE,YISONG XIAO,JIFU ZHENG,XING XU,JUNPING ZHAO,LYSSIKATOS JOSEPH P,HURLEY CHRISTOPHER A,LIU WENDY,LIANG JUN
申请号：
ZA201008957
公开号：
ZA201008957B
申请日:
2010.12.13
申请国别(地区):
ZA
年份:
2014
代理人:
摘要：
A compound of Formula I, enantiomers, diasteriomers, tautomers or pharmaceutically acceptable salts thereof, wherein R1, R2, R3, R4 and R5 are defined herein, are useful as JAK kinase inhibitors. A pharmaceutical composition that includes a compound of Formula I and a pharmaceutically acceptable carrier, adjuvant or vehicle, and methods of treating or lessening the severity of a disease or condition responsive to the inhibition of JAK kinase activity in a patient are disclosed.
