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Imidazopyridine compound
专利权人:
Astellas Pharma Inc.
发明人:
Kurosaki, Toshio,Watanabe, Tsubasa,Ohne, Kazuhiko,Ishioka, Hiroki,Nozawa, Eisuke,Hanazawa, Takeshi,Hachiya, Shunichiro,Shibata, Hiroshi,Koga, Yuji,Mizoguchi, Ryo
申请号:
AU2013353117
公开号:
AU2013353117A1
申请日:
2013.11.28
申请国别(地区):
AU
年份:
2015
代理人:
摘要:
[Problem] To provide a medicinal composition which functions to activate soluble guanylate cyclase (sGC) and which is for the treatment or prevention of various cardiovascular diseases that is based on an improvement in cGMP signals.[Solution] An imidazo[1,2-a]pyridine compound represented by formula (I), which has a carbamoyl group at the 3-position of the imidazo[1,2-a]pyridine framework and has a specific ring group bonded to the 8-position through a methyleneoxy group, or a salt of the compound. The pyridine compound or salt functions to activate sGC and is useful as the active ingredient of a medicinal composition for the treatment or prevention of various cardiovascular diseases in which sGC participates, in particular, peripheral arterial diseases, intermittent claudication, critical limb ischemia, hypertension, and pulmonary hypertension.(In formula (I),A
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/

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