The present invention relates to an active microsphere for tissue repairing microbranches comprising a microsphere body; and a buffer adsorption shell; wherein the buffer adsorption shell is on the outer surface of the microsphere body and completely covers the micro a ball body; a plurality of micro-branches are stacked on the main body of the microsphere, and a plurality of accommodating cavities are disposed between the micro-branches, and the accommodating cavities are connected to each other for transferring a substance; The auxiliary cavity is provided with a plurality of auxiliary active microspheres for active tissue repair (A-co-Collagen).本創作係關於一種用於組織修復具有微枝狀體之活性微球體,包含一微球主體;以及一緩衝吸附殼;其中該緩衝吸附殼在該微球主體外表面,並且完全包覆該微球主體;在該微球主體堆疊有複數個微枝狀體,該微枝狀體之間被設置有複數個容置腔,該容置腔之間相互通連可用來傳遞一物質;及在該容置腔內卡合地設置有複數個輔助活性微球,用於有利組織修復之活性輔媒膠原(Active cofactor collagen;A-co-Collagen)。