The present invention relates to a multifunctional, anhydrous and ozonized phytotherapic composition, consisting of a formulation resulting from the synergy of four suitably mixed and ozonized natural oils: Hypericum Perforatum oil, Prunus Amigdalus Dulcis oil, Calendula Officinalis oil, Echinacea Angustifolia oil and silicon dioxide. The present composition has tissue and bone regenerative properties; it is ideal for the application during post-operative recovery, for the oral cavity and long-term hospitalization. It is also indicated for simple dermatological and cosmetic applications.