The present invention pertains to: an anti-human CRTH2 antibody which specifically recognizes and binds to human CRTH2 a fragment of the antibody DNA which encodes the amino acid sequence of the antibody a vector including the DNA an antibody-producing cell and a hybridoma which produce the antibody a production method for the antibody a composition which includes the antibody or antibody fragment a treatment method and a diagnostic method which use the antibody or antibody fragment for diseases, such as allergenic diseases, autoimmune diseases, diseases associated with eosinophilia and hyperfunction, and diseases associated with an increase in and/or hyperfunction of Th2 cells and a medicine and a diagnostic agent which include the antibody or antibody fragment.