The present invention relates to a stable liquid cabazitaxel formulation in an enclosed container. The enclosed container comprises a liquid phase and an gaseous phase, wherein the liquid phase comprises cabazitaxel, polysorbate 80, ethanol, and one or more pH adjusters to maintain pH about 2.8-6.0, and the gaseous phase is saturated with CO2. The present invention is also directed to a process for preparing the enclosed liquid pharmaceutical composition container.本發明係關於一種在封閉容器中之穩定液態卡巴利他索調配物。該封閉容器包含液相及氣相,其中該液相包含卡巴利他索、聚山梨醇酯80、乙醇及用以維持pH值在約2.8-6.0之一或多種pH調節劑,且該氣相用CO2飽和。本發明亦針對一種用於製備該封閉的液態醫藥組成物容器之方法。