Andreas HAFNER,Fritz BLATTER,Martin SZELAGIEWICZ,Bernd SIEBENHAAR
申请号：
US14169844
公开号：
US20140194453A1
申请日:
2014.01.31
申请国别(地区):
US
年份:
2014
代理人:
摘要：
A novel solid form of Rosuvastatin comprises as the active ingredient a salt of bis[(E)-7-[4-(4-fluorophenyl)-6-isopropyl-2-[methyl(methylsulfonyl)-amino]pyrimidin-5-yl]-(3R,5S)-3,5-dihydroxyhept-6-enoic acid] and vanillin or vanillin derivatives. The crystal comprising the two components, and minor amounts of water, shows improved properties such as crystallization behavior stability and decreased hydroscopic behavior.
