Andreas Hafner,Tobias Hintermann,Fritz Blatter,Eva Roedel
申请号:
US14360799
公开号:
US20150087657A1
申请日:
2012.12.03
申请国别(地区):
US
年份:
2015
代理人:
摘要:
A novel solid form of Voriconazole comprises the active ingredient (2R,3S)-2-(2,4-difluorophenyl)-3-(5-fluoropyrimidin-4-yl)-1-(1H-1,2,4-triazol-1-yl)butan-2-ol and fumaric acid. The solid composition comprising the two components shows improved properties such as water solubility, crystallization behavior and stability.