Siming W. Chen;Dmitri S. Ptchelintsev;Xiaochun Luo
发明人:
Dmitri S. Ptchelintsev,Xiaochun Luo,Siming W. Chen
申请号：
US12747364
公开号：
US08450353B2
申请日:
2008.11.19
申请国别(地区):
US
年份:
2013
代理人:
摘要：
Topical compositions and methods of use to treat symptoms of reduced skin elasticity are provided comprising desthiobiotin and certain desthiobiotin analogues. These compounds are effective in stimulating LOXL-1 activity and can thus increase elastin remodeling and improve appearance of fine lines, wrinkles, skin sagging and other symptoms of reduced elastin function.
