DMIITRI S. PTCHELINTSEV,SIMING W. CHEN,XIAOCHUN LUO
申请号：
BRPI0820815
公开号：
BRPI0820815A2
申请日:
2008.11.19
申请国别(地区):
BR
年份:
2016
代理人:
摘要：
Topical compositions and methods of use to treat symptoms of reduced skin elasticity are provided comprising desthiobiotin and certain desthiobiotin analogues. These compounds are effective in stimulating LOXL-1 activity and can thus increase elastin remodeling and improve appearance of fine lines, wrinkles, skin sagging and other symptoms of reduced elastin function.
