ASHISH B. PATEL,ERIC R. FIRST,GUIDO SCHMITZ,HUNG-HUAR TONG,STEPHANIE PETAWAY-HICKSON
申请号:
BRPI1013509
公开号:
BRPI1013509A2
申请日:
2010.05.10
申请国别(地区):
BR
年份:
2016
代理人:
摘要:
A tablet with an enhanced dissolution profile for a medicinally active ingredient such as aspirin and methods for making the tablet. The tablet comprises a blend of crystals of the medicinally active ingredient and a dissolution aid such as sodium or calcium carbonate or bicarbonate that coats the crystals upon co-milling. The blend is then compressed to form tablets that have an enhanced dissolution profile for the medicinally active ingredient.