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NOVEL SUBSTITUTED IMIDAZOLE DERIVATIVES
专利权人:
MSD K.K.
发明人:
KAWAMURA, MIKAKO,HASHIHAYATA, T.,SUNAMI, SATOSHI,SUGIMOTO, TETSUYA,YAMAMOTO, F.,SATO, Y.,KAMIJO, K.,MITSUYA, M.,IWASAWA, Y.,KOMATANI, H.
申请号:
EP05776832
公开号:
EP1790650B1
申请日:
2005.08.30
申请国别(地区):
EP
年份:
2014
代理人:
摘要:
The present invention relates to a compound represented by Formula [I] or a pharmaceutically acceptable salt or ester thereof:wherein:X1, X2, X3, and X4, which may be identical or different, are each C or N, provided that none to two of X1, X2, X3, and X4 is/are NY is CH or NR1, R1, R2, R2, R3, R3, R4, and R4, which may be identical or different, are each a hydrogen atom, a lower alkyl group, or the likeR5 is a hydrogen atom or a methyl groupR6 and R7, which may be identical or different, are each a hydrogen atom, a lower alkyl group, or the likeR8 and R8, which may be identical or different, are each a hydrogen atom, a lower alkyl group, or the likeR9 is an aryl group or a heteroaryl group which may be substituted andn is an integer from 1 to 3,and a PLK1 inhibitor or an anticancer agent containing the same.
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