The present invention relates to a device for signal compensation in medical X-ray images. The device (100) comprises a generation module (10) configured to generate an X-ray ghosting image based on an X-ray detector read-out subsequent to a last X- ray exposure of a plurality of X-ray exposures; a scaling module (20) configured to scale the X-ray ghosting image into a scaled X-ray ghosting image; and a subtraction module (30) configured to subtract the scaled X-ray ghosting image from any subsequent X-ray image recorded during a respective subsequent X-ray exposure of the plurality of X-ray exposures.