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MODULATION OF ANGIOPOIETIN-LIKE 3 EXPRESSION
专利权人:
发明人:
申请号:
EP11732249.5
公开号:
EP2521556A2
申请日:
2011.01.07
申请国别(地区):
EP
年份:
2012
代理人:
摘要:
Provided herein are methods, compounds, and compositions for reducing expression of an ANGPTL3 mRNA and protein in an animal. Also provided herein are methods, compounds, and compositions for reducing plasma lipids, plasma glucose and atherosclerotic plaques in an animal. Such methods, compounds, and compositions are useful to treat, prevent, delay, or ameliorate any one or more of cardiovascular disease or metabolic disease, or a symptom thereof.
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