CROOKE, Rosanne, M.,GRAHAM, Mark, J.,LEE, Richard,DOBIE, Kenneth, W.
申请号:
DK11732249
公开号:
DK2521556T3
申请日:
2011.01.07
申请国别(地区):
DK
年份:
2018
代理人:
摘要:
Provided herein are methods, compounds, and compositions for reducing expression of an ANGPTL3 mRNA and protein in an animal. Also provided herein are methods, compounds, and compositions for reducing plasma lipids, plasma glucose and atherosclerotic plaques in an animal. Such methods, compounds, and compositions are useful to treat, prevent, delay, or ameliorate any one or more of cardiovascular disease or metabolic disease, or a symptom thereof.